Dupuytren’s Contracture

Dupuytren’s contracture is a diseases which causes one or more fingers to be permanently contractured or bent in a flexed position. It is found to the people with age beyond the fifties and started within the palm as a small nodules just under the skin. It progressively complicated itself until fingers are no longer straitened.

It is causes is not known but it contains many risk factors such as smoking, family history, liver diseases, diabetes and thyroid issues, its pathologic mechanism involves the formation of abnormal connective tissue of the palmar fascia.

Its diagnosis is only based on the symptoms.

Dupuytren contracture can be treated surgically with either open or closed fasciotomy, which will ultimately result in release of contracture on the cords.  A nonsurgical approach consists of intralesional injections with collagenase Clostridium histolyticum.  Which can reduce the contractures and improves range of motion in joints affected by the dupuytren.

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